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Upgrade your microbiome with probiotic-boosting Orafti® Synergy1 Inulin-FOS fiber*

  • Boosts Bifidobacterium probiotics in gut*
  • Supports digestive health, regularity, comfort*
  • Helps immunity, fat loss, nutritional status*
Upgrade Yourself®with Performance Lab® Prebiotic
  • icon-features-allergen-free


  • icon-features-banned-substance-free


  • icon-features-gluten-free


  • icon-features-soy-free


  • Synthetic

  • Caffeine

  • icon-features-non-irradiated


  • icon-features-non-gmo


  • Prebiotic

  • Vegan

  • icon-features-gmp-certified


2-in-1 probiotic + soluble fiber support for healthy metabolic and microbiome performance

Probiotic supplements are unpredictable. They may overload the gut with 20+ billion mixed cultures and lead to gastric distress. Probiotics are also fragile, and may be dead on arrival, failing to help your microbiome.

Prebiotic instead nourishes your existing probiotic colony with Orafti® Synergy1 (Inulin-FOS from chicory root) for robust growth and health.

As a result Prebiotic delivers more reliable, natural and comfortable microbiome support. Plus, fiber support for digestion, immune function, fat loss and more that you don’t get from probiotics.

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Designed for Performance

  • Supports digestive regularity, gut comfort and efficient nutrient absorption*
  • Promotes healthy immune system performance in the GI tract*
  • Nourishes existing gut microbiome rather than introducing new probiotic strains*
  • Helps fat loss by controlling appetite and reducing food caloric density*

Healthy for Daily Use

  • Orafti® Synergy1: Oligofructose-enriched inulin (Inulin-FOS) from chicory root
  • Supports bone health by enhancing calcium absorption*
  • Helps to support heart health by regulating bad cholesterol absorption*
  • 100% natural, prebiotic-infused NutriCaps® from pullulan (fermented tapioca)
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Supplement Facts
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Orafti® Synergy1 Inulin-FOS

Inulin and FOS are soluble fibers with prebiotic properties. Structurally, inulin is a long-chain molecule while FOS is short-chain. Both are found in chicory root, which is 20% inulin and 10% FOS.

Inulin-FOS is resilient: It passes undigested through the GI tract, arriving intact in the colon where it selectively feeds Bifidobacterium probiotic strains and stimulates their growth.


Inulin-FOS Diet Stimulates Bifidus Probiotic Proliferation in the Colon – In vivo study

Performance Lab® Prebiotic Inulin-FOS fiber has been shown in human research to shift Bifidobacteria distribution in the gut from 20% to 71%.

Inulin diet stimulates bifidus probiotic proliferation in the colon.

Why Performance Lab® Prebiotic selectively nourishes Bifidobacterium:

  • Bifidobacterium is suggested to more easily adhere to and reinforce the intestinal lining;
  • Bifidobacterium is a highly competitive probiotic strain, possibly due to enhanced energy-scavenging capacity from a wider variety of nutrients;
  • Bifidobacterium’s superior metabolic performance may outcompete bad bacteria in the gut more efficiently than other probiotic species.

By stimulating robust growth of indigenous Bifidobacterium rather than introducing multiple new probiotic strains, Performance Lab® Prebiotic promotes more organic, comfortable and reliable digestive support.

Together in Prebiotic Orafti® Synergy1, inulin + FOS optimize two key pathways that unlock multiple bio-performance benefits:

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1. Inulin-FOS Probiotic Support

Prebiotic’s Bifidobacterium-promoting activity contributes to probiotic benefits for:

Digestive performance

A robust intestinal microbiome of Bifidobacterium (and other probiotic strains) is important for digestive and metabolic health. Probiotics supply enzymes that enable efficient breakdown and utilization of foods and nutrients in the gut.

Pathogen resistance

Bifidobacterium fermentation of Inulin-FOS produces lactic acid that reduces gut pH, limiting growth of bad bacteria and pathogens such as Candida albacans and E. coli. Bifidobacterium also adheres to the intestinal lining, strengthening a critical barrier against microbes.

Immune function

Probiotics’ anti-pathogen bioactivities support immune function. Probiotics may also promote healthy immune performance by enhancing the synthesis and proliferation of immune cells lymphocytes and macrophages, which play key roles in immune defenses.

Nutritional status

Bifidobacterium and other lactic-acid producing flora promote a favorable acidic environment for absorption of minerals including calcium, magnesium, iron and zinc. Bifidobacterium also synthesizes B-vitamins and vitamin K within the GI tract.

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2. Inulin-FOS Soluble Fiber Support

Prebiotic Inulin-FOS also promotes several soluble fiber benefits for:

Digestive health

  1. Inulin-FOS absorbs water and forms a gel as it passes through the GI tract, softening and bulking stools for easier, more comfortable elimination;
  2. Soluble fiber can help with watery stools, absorbing excess fluid to help form firmer stools and more regular elimination;
  3. Bulkier stools also help with constipation and related straining, which contribute to hemorrhoids and colon health concerns.

Weight control

  1. Inulin-FOS’s ability to absorb water and swell in the stomach blocks the hunger hormone ghrelin and promotes appetite control;
  2. When taken with food and water, Inulin-FOS functionally reduces calorie content of any food item that is consumed;
  3. Taking inulin is suggested to help reduce triglycerides: Building blocks of fatty tissues linked with weight gain and cardiovascular concerns;
  4. Researchers have suggested Inulin-FOS may reduce food intake by suppressing the hunger hormone ghrelin and supporting the satisfaction hormone peptide YY;
  5. Inulin-FOS slows food transit time in the gut, which in turn reduces glycemic load and regulates blood sugar spikes.

Heart health

  1. Soluble fiber from foods such as Inulin-FOS promote heart health by helping to maintain cholesterol levels that are already in normal range;
  2. In the gut, soluble fiber binds cholesterol from foods with bile, thereby limiting cholesterol absorption and encouraging cholesterol elimination.

Performance Lab® Prebiotic Orafti® Synergy1 is oligofructose-enriched inulin fiber from chicory root enhanced with ultramodern nutritional technology. Orafti® Synergy1 has been clinically shown to safely reduce calorie intake and enhance calcium absorption.

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Why Take Performance Lab® Prebiotic instead of a typical probiotic?

Probiotic supplements support healthy intestinal flora, but may have limitations and side effects.

Prebiotic takes a different approach to microflora health that may offer several advantages over standard probiotic supplements:

Probiotic Supplements Performance Lab® Prebiotic Advantage
Introduce multiple new probiotic strains to the gut’s existing microflora colony, sometimes in unnatural ratios that may yield uncomfortable results Feeds the gut’s unique existing microflora colony to promote healthy probiotic growth in harmony with the body, for comfortable and reliable support
Must arrive alive in the colon to confer digestive benefits, but are easily destroyed by heat, cold, light and stomach acid Resilient Orafti® Synergy1 Inulin-FOS fiber passes through the stomach acids unharmed and is fermented by Bifidobacterium in the colon
Some products’ labels claim up to 2+billion ‘live’ cultures, but are shown on analysis to have far fewer, with many cultures ‘dead on arrival’ Always supplying the exact nutrition that is listed on the label, Performance Lab® Prebiotic arrives active and ready to support digestive health
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Who should take Performance Lab® Prebiotic

Prebiotic can be taken by anyone seeking to nourish their microflora to achieve better digestive function and related benefits for weight management, heart health, immunity and more. Prebiotic’s microflora support may be particularly well-suited to those who are dissatisfied with standard probiotic supplements and want to try a new strategy for promoting a robust, healthy and thriving gut microbiome.

How do I take Performance Lab® Prebiotic

For best results take 3 capsules with your first meal of the day, and 3 capsules with your second meal. Always take Prebiotic with at least 8 oz. of water.

Is Performance Lab® Prebiotic safe?

Like all Performance Lab® supplements, Prebiotic is designed to be safe for long-term daily use, without the need for cycling. Prebiotic achieves this by using pure, potent ingredients that are dosed appropriately and in line with clinical research. Prebiotic’s clean formula design – free of GMOs, gluten, soy, colorants, preservatives and other additives – is also well-tolerated by the body, and safe for long-term use.

How is Performance Lab Prebiotic better than a supplement that has 1+ Billion live cultures of 10+ probiotic strains?

Supplements that supply multiple strains of live active cultures in high numbers have many variables that make it hard to predict efficacy and outcomes. More probiotic strains are not necessarily better, and may be associated with undesirable side effects like gas and bloating. High numbers of live active cultures look appealing on a label, but due to the fragility of probiotics and less-than-optimal manufacturing practices of some brands, the actual number of live cultures that reach the colon may be far less.

Performance Lab® Prebiotic takes a different approach: instead of flooding the digestive system with as many different probiotic strains in the highest quantities possible, Prebiotic selectively nourishes a single superior strain that already exists in the gut: Bifidobacterium.

Supplying the ideal nourishment for Bifidobacterium, Prebiotic encourages robust probiotic growth that works in harmony with your unique gut environment – helping to support all the benefits of probiotics more comfortably, organically and reliably than some probiotic supplements.

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Performance Lab® Prebiotic

Ready to upgrade your gut? Take Performance Lab® Prebiotic for microbiome + fiber support that helps digestion, nutritional status, immune function and more.

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30-Day Performance Promise

Your first order of any Performance Lab® product is covered by our 30-day performance promise.

Put Performance Lab® Prebiotic to the test for a full 30 days and if you don’t see results, we’ll refund your money. No questions asked.

Simply get in touch with a member of our Customer Care team to arrange the return of the empty bottle, and any unused bottles.

The Performance Lab® Performance Promise covers one box of any of our products, up to a maximum of three products per order.

Price Promise

Prebiotic stacks well with…

NutriGenesis® Multi for Men

Prebiotic + NutriGenesis® Multi for Men

NutriGenesis® Multi vitamins and minerals optimize body cells, systems and organs for healthy function.

Prebiotic nourishes gut Bifidobacterium that enhance NutriGenesis® Multi nutrients’ absorption and help with natural synthesis of B-vitamins and vitamin K.

Take Prebiotic + NutriGenesis® Multi as a complementary stack for bio-performance and overall health.

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NutriGenesis® Multi for Women

Prebiotic + NutriGenesis® Multi for Women

NutriGenesis® Multi vitamins and minerals optimize body cells, systems and organs for healthy function.

Prebiotic nourishes gut Bifidobacterium that enhance NutriGenesis® Multi nutrients’ absorption and help with natural synthesis of B-vitamins and vitamin K.

Take Prebiotic + NutriGenesis® Multi as a complementary stack for bio-performance and overall health.

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Prebiotic + Energy

Energy is a stim-free vitality formula that boosts cells’ powerhouse mitochondria.

It combines with Prebiotic to provide far-reaching metabolic support that enhances nutrient utilization on a cellular level.

Take Energy + Prebiotic as a stim-free stack for natural vitality and healthy metabolic performance.

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Prebiotic + Burn

SPORT Burn’s muscle-sparing thermogenic design helps maximize fat loss.

Prebiotic enhances SPORT Burn results by assisting with appetite control and nutrient metabolism.

Take SPORT Burn + Prebiotic to support weight loss via multiple complementary pathways, without harsh synthetics or stimulants.

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Prebiotic + Protein

SPORT Protein supplies organic-certified rice protein that enhances muscle strength, power, growth and performance.

Prebiotic helps SPORT Protein to work even better by nourishing Bifidobacterium that metabolize proteins and amino acids.

Take Prebiotic + SPORT Protein as a foundational stack for ideal body composition and healthy nutritional status.

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The research and studies behind Performance Lab® Prebiotic.

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Jürgen Schrezenmeir and Michael de Vrese. Probiotics, prebiotics, and synbiotics—approaching a definition . Am J Clin Nutr February 2001 vol. 73 no. 2 361s-364s
Abrams SA, Griffin IJ, Hawthorne KM, Liang L, Gunn SK, Darlington G, Ellis KJ. (2005) A combination of prebiotic short- and long-chain Inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents . Am. J. Clin. Nutr., 82: 471-6.
Kelly G. Inulin-type prebiotics--a review: part 1 . Altern Med Rev. 2008 Dec;13(4):315-29.
Slavin J. Fiber and prebiotics: Mechanisms and Health Benefits . Nutrients. 2013 Apr; 5(4): 1417–1435.
Niness K. J. Inulin and Oligofructose: What Are They? Nutr. July 1, 1999 vol. 129 no. 7 1402S-1406s
Kaur N, Gupta AK. Applications of inulin and oligofructose in health and nutrition . J Biosci. 2002 Dec;27(7):703-14.
Roberfroid MB. Introducing inulin-type fructans . Br J Nutr. 2005 Apr;93 Suppl 1:S13-25.
Seifert S1, Watzl B. Inulin and oligofructose: review of experimental data on immune modulation . J Nutr. 2007 Nov;137(11 Suppl):2563S-2567S.
Cani PD, Joly E, Horsmans Y, Delzenne NM. (2006) Oligofructose promotes satiety in healthy human: a pilot study. Eur. J. Clin. Nutr., 60: 567-72.
Gibson, G. R., Beatty, E. R., Wang, X. & Cummings, J. H. (1995) Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin . Gastroenterology 108:975-982.
Gibson, G. R. & Roberfroid, M.B. (1995) Dietary modulation of the human colonic microbiota—introducing the concept of prebiotics . J. Nutr. 125:1401-1412
Abrams SA, Griffin IJ, Hawthorne KM, Ellis KJ. (2007) Effect of prebiotic supplementation and calcium intake on body mass index . J. Pediatr., 151: 293-8.
Bouhnik Y, Raskine L, Champion K, Andrieux C, Penven S, Jacobs H , Simoneau G. (2007) Prolonged administration of low-dose inulin stimulates the growth of bifidobacteria in humans . Nutr. Res., 27: 187-193.
Langlands S, Hopkins M, Coleman N, Cummings J. (2004) Prebiotic carbohydrates modify the mucosa associated microflora of the human large bowel . Gut, 53: 1610-16.
Ramirez-Farias C, Slezak K, Fuller Z, Duncan A, Holtrop G, Louis P. (2009) Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii . Brit. J. Nutr., 101: 541-50.
Menne E, Guggenbuhl N, Roberfroid M (2000) Fn-type chichory inulin hydrolysate has a prebiotic effect in humans . J. Nutr., 130:1197-99.
Dewulf EM, Cani PD, Claus SP, Fuentes S, Puylaert PGB, Neyrinck A, Bindels LB, de Vos WM, Gibson GR, Thissen JP,
Woodmansey EJ. (2007). Intestinal bacteria and ageing . J Appl Microbiol., May;102(5):1178-86.
Matsuzaki T, Chin J. (2000). Modulating immune responses with probiotic bacteria . Immunology and Cell Biology, 78, 67–73.
LeBlanc JG, et al. (2011). B-group vitamin production by lactic acid bacteria--current knowledge and potential applications . J Appl Microbiol. Dec;111(6):1297-309.
Dinan TG, Stanton C, Cryan JF. Psychobiotics: a novel class of psychotropic . Biol Psychiatry. 2013 Nov 15;74(10):720-6.
Cryan JF and Dinan TG. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour . Nat Rev Neurosci. 2012 Oct;13(10):701-12.
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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.